2023
Rheaume, BA, Xing, J., Lukomska, A, Theune, WC, Damania, A, Sjogren, G, Trakhtenberg, EF. Long-distance axon regeneration promoted by PTEN inhibition is associated with differentiation of M1 ipRGCs and upregulation of mitochondrial DYNLT1A and LARS2. Development 2023 (In press)
Ta A, Ricci-Azevedo R, Vasudevan SO, Wright SS, Kumari P, Havira MS, Nair MS, Rathinam VA, Vanaja SK. A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3. Nat Commun. 2023 (Accepted)
Ferraj A, Audano PA, Balachandran P, Czechanski A, Flores JI, Radecki AA, Mosur V, Gordon DS, Walawalkar IA, Eichler EE, Reinholdt LG, Beck CR. Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements. Cell Genomics 2023 https://doi.org/10.1016/j.xgen.2023.100291
Wang C, Shivcharan S, Tian T, Wright SS, Danyang M, Chang J, Li K, Song K, Xu C, Rathinam VA, Ruan J. Structural basis for GSDMB pore formation and its targeting by IpaH7.8. Nature 2023 https://doi.org/10.1038/s41586-023-05832-z
Sutter PA, Willis CM, Menoret A, Nicaise AM, Sacino A, Sikkema AH, Jellison E, Win KK, Han DK, Church W, Baron W, Vella AT, Crocker SJ. Astrocytic TIMP-1 regulates production of Anastellin, a novel inhibitor of oligodendrocyte differentiation and FTY720 responses. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529003. doi: 10.1101/2023.02.17.529003. PMID: 36824834; PMCID: PMC9949145.
Benoit MR, Darboe M, Das B, Ge Y, Zhou J, Yao A, He W, Yan R, Hu X. Postnatal neuronal Bace1 deletion impairs neuroblast and oligodendrocyte maturation. Hum Mol Genet. 2023 Mar 20;32(7):1193-1207. doi: 10.1093/hmg/ddac282. PMID: 36370042; PMCID: PMC10026251.
Masison J, Mendes P. Modeling the iron storage protein ferritin reveals how residual ferrihydrite iron determines initial ferritin iron sequestration kinetics. PLoS One. 2023 Feb 6;18(2):e0281401. doi: 10.1371/journal.pone.0281401. PMID: 36745660; PMCID: PMC9901743.
Matz AJ, Qu L, Karlinsey K, Vella AT, Zhou B. Capturing the multifaceted function of adipose tissue macrophages. Front Immunol. 2023 Feb 16;14:1148188. doi: 10.3389/fimmu.2023.1148188. PMID: 36875144; PMCID: PMC9977801.
Cohn RL, Gasek NS, Kuchel GA, Xu M. The heterogeneity of cellular senescence: insights at the single-cell level. Trends Cell Biol. 2023 Jan;33(1):9-17. doi: 10.1016/j.tcb.2022.04.011. Epub 2022 May 20. PMID: 35599179; PMCID: PMC9812642.
Doherty L, Wan M, Peterson A, Youngstrom DW, King JS, Kalajzic I, Hankenson KD, Sanjay A. Wnt-associated adult stem cell marker Lgr6 is required for osteogenesis and fracture healing. Bone. 2023 Apr;169:116681. doi: 10.1016/j.bone.2023.116681. Epub 2023 Jan 25. PMID: 36708855; PMCID: PMC10015414.
Xing J*, Lukomska A*, Rheaume BA*, Kim J, Sajid MS, Damania A, Trakhtenberg EF. Post-injury born oligodendrocytes incorporate into the glial scar and contribute to the inhibition of axon regeneration. Development. 2023 Mar 27:dev.201311. doi: 10.1242/dev.201311. Epub ahead of print. PMID: 36971369.
Ménoret A, Agliano F, Karginov TA, Karlinsey KS, Zhou B, Vella AT. Antigen-specific downregulation of miR-150 in CD4 T cells promotes cell survival. Front Immunol. 2023 Jan 27;14:1102403. doi: 10.3389/fimmu.2023.1102403. PMID: 36817480; PMCID: PMC9936563.
Mason H, Rai G, Kozyr A, De Jonge N, Gliniewicz E, Berg LJ, Wald G, Dorrier C, Henderson MJ, Zakharov A, Dyson T, Audley J, Pettinato AM, Padilha EC, Shah P, Xu X, Leto TL, Simeonov A, Zarember KA, McGavern DB, Gallin JI. Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury. Redox Biol. 2023 Apr;60:102611. doi: 10.1016/j.redox.2023.102611. Epub 2023 Jan 18. PMID: 36709665; PMCID: PMC9894920.
Krishnan N, McMullan P, Yang Q, Buscarello AN, Germain-Lee EL. Prevalence of Chiari malformation type 1 is increased in pseudohypoparathyroidism type 1A and associated with aberrant bone development. PLoS One. 2023 Jan 20;18(1):e0280463. doi: 10.1371/journal.pone.0280463. PMID: 36662765; PMCID: PMC9858345.
LaGree TJ, Byrd BA, Quelle RM, Schofield SL, Mok WWK. Stimulating Transcription in Antibiotic-Tolerant Escherichia coli Sensitizes It to Fluoroquinolone and Nonfluoroquinolone Topoisomerase Inhibitors. Antimicrob Agents Chemother. 2023 Mar 23:e0163922. doi: 10.1128/aac.01639-22. Epub ahead of print. PMID: 36951560.
2022
McMullan P, Germain-Lee EL. Aberrant Bone Regulation in Albright Hereditary Osteodystrophy dueto Gnas Inactivation: Mechanisms and Translational Implications. Curr Osteoporos Rep. 2022 Feb;20(1):78-89. doi: 10.1007/s11914-022-00719-w. Epub 2022 Feb 28. PMID: 35226254.
Madden-Hennessey K, Gupta D, Radecki AA, Guild C, Rath A, Heinen CD. Loss of mismatch repair promotes a direct selective advantage in human stem cells. Stem Cell Reports. 2022 Dec 13;17(12):2661-2673. doi: 10.1016/j.stemcr.2022.10.009. Epub 2022 Nov 10. PMID: 36368329; PMCID: PMC9768573.
Wang B, Wang L, Gasek NS, Zhou Y, Kim T, Guo C, Jellison ER, Haynes L, Yadav S, Tchkonia T, Kuchel GA, Kirkland JL, Xu M. An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo. Nat Aging. 2021 Oct;1(10):962-973. doi: 10.1038/s43587-021-00107-6. Epub 2021 Oct 7. PMID: 35024619; PMCID: PMC8746571.
Karlinsey K, Matz A, Qu L, Zhou B. Extracellular RNAs from immune cells under obesity-a narrative review. ExRNA. 2022 Aug 30;4:18. doi: 10.21037/exrna-22-15. PMID: 36866026; PMCID: PMC9977143.
Karginov TA, Ménoret A, Vella AT. Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape. Nat Commun. 2022 Jun 20;13(1):3540. doi: 10.1038/s41467-022-31228-0. PMID: 35725727; PMCID: PMC9209503.
Pettinato AM, Ladha FA, Zeman J, Ingrassia JJ. Spontaneous Coronary Artery Dissection Following SARS-CoV-2-Associated Multisystem Inflammatory Syndrome. Cureus. 2022 Jul 1;14(7):e26479. doi: 10.7759/cureus.26479. PMID: 35919216; PMCID: PMC9339137.
Gayen M, Benoit MR, Fan Q, Hudobenko J, Yan R. The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling. J Biol Chem. 2022 Nov;298(11):102532. doi: 10.1016/j.jbc.2022.102532. Epub 2022 Sep 24. PMID: 36162508; PMCID: PMC9626938.
Wright SS, Vanaja SK. Shigella "Osp"pression of innate immunity. Cell. 2022 Jun 23;185(13):2205-2207. doi: 10.1016/j.cell.2022.05.027. PMID: 35750030.
Ladha FA, Pettinato AM, Perrin AE. Medical student residency preferences and motivational factors: a longitudinal, single-institution perspective. BMC Med Educ. 2022 Mar 17;22(1):187. doi: 10.1186/s12909-022-03244-7. PMID: 35300656; PMCID: PMC8929265.
Li C, Phoon YP, Karlinsey K, Tian YF, Thapaliya S, Thongkum A, Qu L, Matz AJ, Cameron M, Cameron C, Menoret A, Funchain P, Song JM, Diaz-Montero CM, Tamilselvan B, Golden JB, Cartwright M, Rodriguez A, Bonin C, Vella A, Zhou B, Gastman BR. A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients. J Exp Med. 2022 Jan 3;219(1):e20202084. doi: 10.1084/jem.20202084. Epub 2021 Nov 22. PMID: 34807232; PMCID: PMC8611729.
Rosina M, Ceci V, Turchi R, Chuan L, Borcherding N, Sciarretta F, Sánchez-Díaz M, Tortolici F, Karlinsey K, Chiurchiù V, Fuoco C, Giwa R, Field RL, Audano M, Arena S, Palma A, Riccio F, Shamsi F, Renzone G, Verri M, Crescenzi A, Rizza S, Faienza F, Filomeni G, Kooijman S, Rufini S, de Vries AAF, Scaloni A, Mitro N, Tseng YH, Hidalgo A, Zhou B, Brestoff JR, Aquilano K, Lettieri-Barbato D. Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue. Cell Metab. 2022 Apr 5;34(4):533-548.e12. doi: 10.1016/j.cmet.2022.02.016. Epub 2022 Mar 18. PMID: 35305295; PMCID: PMC9039922.
Guan C, Larson PJ, Fleming E, Tikhonov AP, Mootien S, Grossman TH, Golino C, Oh J. Engineering a "detect and destroy" skin probiotic to combat methicillin-resistant Staphylococcus aureus. PLoS One. 2022 Dec 15;17(12):e0276795. doi: 10.1371/journal.pone.0276795. PMID: 36520793; PMCID: PMC9754240.
Wang L, Wang B, Gasek NS, Zhou Y, Cohn RL, Martin DE, Zuo W, Flynn WF, Guo C, Jellison ER, Kim T, Prata LGPL, Palmer AK, Li M, Inman CL, Barber LS, Al-Naggar IMA, Zhou Y, Du W, Kshitiz, Kuchel GA, Meves A, Tchkonia T, Kirkland JL, Robson P, Xu M. Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity. Cell Metab. 2022 Jan 4;34(1):75-89.e8. doi: 10.1016/j.cmet.2021.11.002. Epub 2021 Nov 22. Erratum in: Cell Metab. 2022 Jan 4;34(1):186. PMID: 34813734; PMCID: PMC8732323.
Forte E, Ramialison M, Nim HT, Mara M, Li JY, Cohn R, Daigle SL, Boyd S, Stanley EG, Elefanty AG, Hinson JT, Costa MW, Rosenthal NA, Furtado MB. Adult mouse fibroblasts retain organ-specific transcriptomic identity. Elife. 2022 Mar 16;11:e71008. doi: 10.7554/eLife.71008. PMID: 35293863; PMCID: PMC8959603.
Gasek NS, Kuchel GA, Kirkland JL, Xu M. Strategies for Targeting Senescent Cells in Human Disease. Nat Aging. 2021 Oct;1(10):870-879. doi: 10.1038/s43587-021-00121-8. Epub 2021 Oct 7. PMID: 34841261; PMCID: PMC8612694.
Larson PJ, Zhou W, Santiago A, Driscoll S, Fleming E, Voigt AY, Chun OK, Grady JJ, Kuchel GA, Robison JT, Oh J. Associations of the skin, oral and gut microbiome with aging, frailty and infection risk reservoirs in older adults. Nat Aging. 2022 Oct;2(10):941-955. doi: 10.1038/s43587-022-00287-9. Epub 2022 Oct 12. PMID: 36398033; PMCID: PMC9667708.
Pettinato AM, Ladha FA, Hinson JT. The Cardiac Sarcomere and Cell Cycle. Curr Cardiol Rep. 2022 Jun;24(6):623-630. doi: 10.1007/s11886-022-01682-9. Epub 2022 Apr 5. PMID: 35380383.
Chen I, Chung J, Vella R, Weinstock GM, Zhou Y, Jheon AH. Alterations in subgingival microbiota during full-fixed appliance orthodontic treatment-A prospective study. Orthod Craniofac Res. 2022 May;25(2):260-268. doi: 10.1111/ocr.12534. Epub 2021 Sep 25. PMID: 34538018.
Romano R, Ghahremani S, Zimmerman T, Legere N, Thakar K, Ladha FA, Pettinato AM, Hinson JT. Reading Frame Repair of TTN Truncation Variants Restores Titin Quantity and Functions. Circulation. 2022 Jan 18;145(3):194-205. doi: 10.1161/CIRCULATIONAHA.120.049997. Epub 2021 Dec 14. PMID: 34905694; PMCID: PMC8766920.
Urbanski L, Brugiolo M, Park S, Angarola BL, Leclair NK, Yurieva M, Palmer P, Sahu SK, Anczuków O. MYC regulates a pan-cancer network of co-expressed oncogenic splicing factors. Cell Rep. 2022 Nov 22;41(8):111704. doi: 10.1016/j.celrep.2022.111704. PMID: 36417849; PMCID: PMC9731204.
Martinez EC, Li J, Ataam JA, Tokarski K, Thakur H, Karakikes I, Dodge-Kafka K, Kapiloff MS. Targeting mAKAPβ expression as a therapeutic approach for ischemic cardiomyopathy. Gene Ther. 2022 Feb 1:10.1038/s41434-022-00321-w. doi: 10.1038/s41434-022-00321-w. Epub ahead of print. PMID: 35102273; PMCID: PMC9339585.
Sutter PA, Crocker SJ. Glia as antigen-presenting cells in the central nervous system. Curr Opin Neurobiol. 2022 Dec;77:102646. doi: 10.1016/j.conb.2022.102646. Epub 2022 Nov 10. PMID: 36371828.
Rouillard ME, Hu J, Sutter PA, Kim HW, Huang JK, Crocker SJ. The Cellular Senescence Factor Extracellular HMGB1 Directly Inhibits Oligodendrocyte Progenitor Cell Differentiation and Impairs CNS Remyelination. Front Cell Neurosci. 2022 Apr 28;16:833186. doi: 10.3389/fncel.2022.833186. PMID: 35573828; PMCID: PMC9095917.
Paro M, Lambert WA, Leclair NK, Romano R, Stoltz P, Martin JE, Hersh DS, Bookland MJ. Machine Learning-Driven Clinical Image Analysis to Identify Craniosynostosis: A Pilot Study of Telemedicine and Clinic Patients. Neurosurgery. 2022 May 1;90(5):613-618. doi: 10.1227/neu.0000000000001890. PMID: 35262516.
DiScipio KA, Weerasooriya S, Szczepaniak R, Hazeen A, Wright LR, Wright DL, Weller SK. Two-Metal Ion-Dependent Enzymes as Potential Antiviral Targets in Human Herpesviruses. mBio. 2022 Feb 22;13(1):e0322621. doi: 10.1128/mbio.03226-21. Epub 2022 Jan 25. PMID: 35073739; PMCID: PMC8787488.
Leclair NK, Lambert WA, Wu Q, Wolansky L, Becker K, Li L, Leishangthem L, Bulsara KR. Genomic sequencing of a pregnancy associated symptomatic meningioma of the diaphragma sellae: a case report. Br J Neurosurg. 2022 Jan 8:1-5. doi: 10.1080/02688697.2021.2024503. Epub ahead of print. PMID: 35001774.
Pettinato AM, Yoo D, VanOudenhove J, Chen YS, Cohn R, Ladha FA, Yang X, Thakar K, Romano R, Legere N, Meredith E, Robson P, Regnier M, Cotney JL, Murry CE, Hinson JT. Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment. Cell Rep. 2021 May 4;35(5):109088. doi: 10.1016/j.celrep.2021.109088. PMID: 33951429; PMCID: PMC8161465.
Larson PJ, Chong D, Fleming E, Oh J. Challenges in Developing a Human Model System for Skin Microbiome Research. J Invest Dermatol. 2021 Jan;141(1):228-231.e4. doi: 10.1016/j.jid.2020.05.096. Epub 2020 Jun 6. PMID: 32522484; PMCID: PMC7719096.
Martinek J, Lin J, Kim KI, Wang VG, Wu TC, Chiorazzi M, Boruchov H, Gulati A, Seeniraj S, Sun L, Marches F, Robson P, Rongvaux A, Flavell RA, George J, Chuang JH, Banchereau J, Palucka K. Transcriptional profiling of macrophages in situ in metastatic melanoma reveals localization-dependent phenotypes and function. Cell Rep Med. 2022 May 17;3(5):100621. doi: 10.1016/j.xcrm.2022.100621. Epub 2022 Apr 27. PMID: 35584631; PMCID: PMC9133468.
Balachandran P, Walawalkar IA, Flores JI, Dayton JN, Audano PA, Beck CR. Transposable element-mediated rearrangements are prevalent in human genomes. Nat Commun. 2022 Nov 19;13(1):7115. doi: 10.1038/s41467-022-34810-8. PMID: 36402840; PMCID: PMC9675761.
Marazzi L, Shah M, Balakrishnan S, Patil A, Vera-Licona P. NETISCE: a network-based tool for cell fate reprogramming. NPJ Syst Biol Appl. 2022 Jun 20;8(1):21. doi: 10.1038/s41540-022-00231-y. PMID: 35725577; PMCID: PMC9209484.
Wright SS, Vasudevan SO, Rathinam VA. Mechanisms and Consequences of Noncanonical Inflammasome-Mediated Pyroptosis. J Mol Biol. 2022 Feb 28;434(4):167245. doi: 10.1016/j.jmb.2021.167245. Epub 2021 Sep 16. PMID: 34537239; PMCID: PMC8844060.
Yu CI, Martinek J, Wu TC, Kim KI, George J, Ahmadzadeh E, Maser R, Marches F, Metang P, Authie P, Oliveira VKP, Wang VG, Chuang JH, Robson P, Banchereau J, Palucka K. Human KIT+ myeloid cells facilitate visceral metastasis by melanoma. J Exp Med. 2021 Jun 7;218(6):e20182163. doi: 10.1084/jem.20182163. PMID: 33857287; PMCID: PMC8056753.
Agliano F, Karginov TA, Ménoret A, Provatas A, Vella AT. Nicotinamide breaks effector CD8 T cell responses by targeting mTOR signaling. iScience. 2022 Feb 15;25(3):103932. doi: 10.1016/j.isci.2022.103932. PMID: 35243268; PMCID: PMC8886054.
Schaufler C, Daigle R, Singhaviranon S, Gjertson CK, Albertsen PC, Ristau BT. How many cores are enough? Optimizing the transperineal prostate biopsy template. Urol Oncol. 2022 May;40(5):191.e1-191.e7. doi: 10.1016/j.urolonc.2021.11.026. Epub 2022 Jan 20. PMID: 35067430.
Hensel JA, Nicholas SE, Kimble AL, Nagpal AS, Omar OMF, Tyburski JD, Jellison ER, Ménoret A, Ozawa M, Rodriguez-Oquendo A, Vella AT, Murphy PA. Splice factor polypyrimidine tract-binding protein 1 (Ptbp1) primes endothelial inflammation in atherogenic disturbed flow conditions. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2122227119. doi: 10.1073/pnas.2122227119. Epub 2022 Jul 18. PMID: 35858420; PMCID: PMC9335344.
2021
Byrd BA, Zenick B, Rocha-Granados MC, Englander HE, Hare PJ, LaGree TJ, DeMarco AM, Mok WWK. The AcrAB-TolC Efflux Pump Impacts Persistence and Resistance Development in Stationary-Phase Escherichia coli following Delafloxacin Treatment. Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0028121. doi: 10.1128/AAC.00281-21. Epub 2021 Jul 16. PMID: 34097492; PMCID: PMC8284433.
Fleming E, Pabst V, Scholar Z, Xiong R, Voigt AY, Zhou W, Hoyt A, Hardy R, Peterson A, Beach R, Ondouah-Nzutchi Y, Dong J, Bateman L, Vernon SD, Oh J. Cultivation of common bacterial species and strains from human skin, oral, and gut microbiota. BMC Microbiol. 2021 Oct 14;21(1):278. doi: 10.1186/s12866-021-02314-y. PMID: 34649516; PMCID: PMC8515726.
Lukomska A*, Kim J*, Rheaume BA*, Xing J, Hoyt A, Lecky E, Steidl T, Trakhtenberg EF. Developmentally upregulated transcriptional elongation factor a like 3 suppresses axon regeneration after optic nerve injury. Neurosci Lett. 2021 Nov 20;765:136260. doi: 10.1016/j.neulet.2021.136260. Epub 2021 Sep 21. PMID: 34560191; PMCID: PMC8572158.
Reilly SK, Gosai SJ, Gutierrez A, Mackay-Smith A, Ulirsch JC, Kanai M, Mouri K, Berenzy D, Kales S, Butler GM, Gladden-Young A, Bhuiyan RM, Stitzel ML, Finucane HK, Sabeti PC, Tewhey R. Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR-FlowFISH. Nat Genet. 2021 Aug;53(8):1166-1176. doi: 10.1038/s41588-021-00900-4. Epub 2021 Jul 29. Erratum in: Nat Genet. 2021 Oct;53(10):1517. PMID: 34326544; PMCID: PMC8925018.
Ebrahimi-Nik H, Moussa M, Englander RP, Singhaviranon S, Michaux J, Pak H, Miyadera H, Corwin WL, Keller GLJ, Hagymasi AT, Shcheglova TV, Coukos G, Baker BM, Mandoiu II, Bassani-Sternberg M, Srivastava PK. Reversion analysis reveals the in vivo immunogenicity of a poorly MHC I-binding cancer neoepitope. Nat Commun. 2021 Nov 5;12(1):6423. doi: 10.1038/s41467-021-26646-5. PMID: 34741035; PMCID: PMC8571378.
Brennick CA, George MM, Moussa MM, Hagymasi AT, Seesi SA, Shcheglova TV, Englander RP, Keller GL, Balsbaugh JL, Baker BM, Schietinger A, Mandoiu II, Srivastava PK. An unbiased approach to defining bona fide cancer neoepitopes that elicit immune-mediated cancer rejection. J Clin Invest. 2021 Feb 1;131(3):e142823. doi: 10.1172/JCI142823. PMID: 33320837; PMCID: PMC7843235.
Das B, Singh N, Yao AY, Zhou J, He W, Hu X, Yan R. BACE1 controls synaptic function through modulating release of synaptic vesicles. Mol Psychiatry. 2021 Nov;26(11):6394-6410. doi: 10.1038/s41380-021-01166-2. Epub 2021 Jun 22. PMID: 34158621; PMCID: PMC8760050.
Hare PJ, LaGree TJ, Byrd BA, DeMarco AM, Mok WWK. Single-Cell Technologies to Study Phenotypic Heterogeneity and Bacterial Persisters. Microorganisms. 2021 Nov 1;9(11):2277. doi: 10.3390/microorganisms9112277. PMID: 34835403; PMCID: PMC8620850.
Ladha FA, Thakar K, Pettinato AM, Legere N, Ghahremani S, Cohn R, Romano R, Meredith E, Chen YS, Hinson JT. Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2. Cell Rep. 2021 Aug 10;36(6):109512. doi: 10.1016/j.celrep.2021.109512. PMID: 34380038; PMCID: PMC8447243.
McMullan P, Maye P, Yang Q, Rowe DW, Germain-Lee EL. Parental Origin of Gsα Inactivation Differentially Affects Bone Remodeling in a Mouse Model of Albright Hereditary Osteodystrophy. JBMR Plus. 2021 Nov 16;6(1):e10570. doi: 10.1002/jbm4.10570. PMID: 35079678; PMCID: PMC8771002.
2020
Bargagna-Mohan P, Schultz G, Rheaume B, Trakhtenberg EF, Robson P, Pal-Ghosh S, Stepp MA, Given KS, Macklin WB, Mohan R. Corneal nonmyelinating Schwann cells illuminated by single-cell transcriptomics and visualized by protein biomarkers. J Neurosci Res. 2021 Mar;99(3):731-749. doi: 10.1002/jnr.24757. Epub 2020 Nov 16. PMID: 33197966; PMCID: PMC7894186.
Zhou Y, Al-Naggar IMA, Chen PJ, Gasek NS, Wang K, Mehta S, Kuchel GA, Yadav S, Xu M. Senolytics alleviate the degenerative disorders of temporomandibular joint in old age. Aging Cell. 2021 Jul;20(7):e13394. doi: 10.1111/acel.13394. Epub 2021 Jun 8. PMID: 34101970; PMCID: PMC8282237.
Sutter PA, Karki S, Crawley I, Singh V, Bernt KM, Rowe DW, Crocker SJ, Bayarsaihan D, Guzzo RM. Mesenchyme-specific loss of Dot1L histone methyltransferase leads to skeletal dysplasia phenotype in mice. Bone. 2021 Jan;142:115677. doi: 10.1016/j.bone.2020.115677. Epub 2020 Oct 3. PMID: 33022452; PMCID: PMC7744341.
Leclair NK, Lambert WA, Knopf J, Stoltz P, Hersh DS, Martin JE, Bookland MJ. Rate of craniometric change following suture release in patients with metopic and sagittal craniosynostosis. J Neurosurg Pediatr. 2021 Oct 1;29(1):66-73. doi: 10.3171/2021.7.PEDS21239. PMID: 34598147.
Lambert WA, Leclair NK, Knopf J, Mosha MH, Bookland MJ, Martin JE, Hersh DS. Predictors of Telemedicine Utilization in a Pediatric Neurosurgical Population During the COVID-19 Pandemic. World Neurosurg. 2021 Sep;153:e308-e314. doi: 10.1016/j.wneu.2021.06.120. Epub 2021 Jul 2. PMID: 34224882; PMCID: PMC9760262.
Kumari P, Russo AJ, Wright SS, Muthupalani S, Rathinam VA. Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense. Cell Rep. 2021 Apr 20;35(3):109012. doi: 10.1016/j.celrep.2021.109012. PMID: 33882312; PMCID: PMC8451177.
Willis CM, Nicaise AM, Bongarzone ER, Givogri M, Reiter CR, Heintz O, Jellison ER, Sutter PA, TeHennepe G, Ananda G, Vella AT, Crocker SJ. Astrocyte Support for Oligodendrocyte Differentiation can be Conveyed via Extracellular Vesicles but Diminishes with Age. Sci Rep. 2020 Jan 21;10(1):828. doi: 10.1038/s41598-020-57663-x. PMID: 31964978; PMCID: PMC6972737.
Marazzi L, Gainer-Dewar A, Vera-Licona P. OCSANA+: optimal control and simulation of signaling networks from network analysis. Bioinformatics. 2020 Dec 8;36(19):4960-4962. doi: 10.1093/bioinformatics/btaa625. PMID: 32879935.
Marazzi L, Kohli P, Eastman D. Transcriptome dataset for RNA-seq analysis of axolotl embryonic oropharyngeal endoderm explants. Data Brief. 2020 Aug 4;32:106126. doi: 10.1016/j.dib.2020.106126. PMID: 32802925; PMCID: PMC7419325.
Leclair NK, Brugiolo M, Urbanski L, Lawson SC, Thakar K, Yurieva M, George J, Hinson JT, Cheng A, Graveley BR, Anczuków O. Poison Exon Splicing Regulates a Coordinated Network of SR Protein Expression during Differentiation and Tumorigenesis. Mol Cell. 2020 Nov 19;80(4):648-665.e9. doi: 10.1016/j.molcel.2020.10.019. Epub 2020 Nov 10. PMID: 33176162; PMCID: PMC7680420.
Ladha FA, Stitzel ML, Hinson JT. From GWAS Association to Function: Candidate Gene Screening Within Insulin Resistance-Associated Genomic Loci Using a Preadipocyte Differentiation Model. Circ Res. 2020 Jan 31;126(3):347-349. doi: 10.1161/CIRCRESAHA.119.316405. Epub 2020 Jan 30. PMID: 31999535; PMCID: PMC7000166.
Pettinato AM, Ladha FA, Mellert DJ, Legere N, Cohn R, Romano R, Thakar K, Chen YS, Hinson JT. Development of a Cardiac Sarcomere Functional Genomics Platform to Enable Scalable Interrogation of Human TNNT2 Variants. Circulation. 2020 Dec 8;142(23):2262-2275. doi: 10.1161/CIRCULATIONAHA.120.047999. Epub 2020 Oct 7. PMID: 33025817; PMCID: PMC7722228.
Fan Q, He W, Gayen M, Benoit MR, Luo X, Hu X, Yan R. Activated CX3CL1/Smad2 Signals Prevent Neuronal Loss and Alzheimer's Tau Pathology-Mediated Cognitive Dysfunction. J Neurosci. 2020 Jan 29;40(5):1133-1144. doi: 10.1523/JNEUROSCI.1333-19.2019. Epub 2019 Dec 10. PMID: 31822518; PMCID: PMC6989010.
Zhou W, Spoto M, Hardy R, Guan C, Fleming E, Larson PJ, Brown JS, Oh J. Host-Specific Evolutionary and Transmission Dynamics Shape the Functional Diversification of Staphylococcus epidermidis in Human Skin. Cell. 2020 Feb 6;180(3):454-470.e18. doi: 10.1016/j.cell.2020.01.006. Epub 2020 Jan 30. PMID: 32004459; PMCID: PMC7192218.
Srivastava A, Das B, Yao AY, Yan R. Metabotropic Glutamate Receptors in Alzheimer's Disease Synaptic Dysfunction: Therapeutic Opportunities and Hope for the Future. J Alzheimers Dis. 2020;78(4):1345-1361. doi: 10.3233/JAD-201146. PMID: 33325389; PMCID: PMC8439550.
Agliano F, Karlinsey KS, Ragazzi M, Ménoret A, Vella AT. A benzimidazole inhibitor attenuates sterile inflammation induced in a model of systemic autoinflammation in female mice. Sci Rep. 2020 Jul 21;10(1):12100. doi: 10.1038/s41598-020-68985-1. PMID: 32694575; PMCID: PMC7374700.
Muñoz CX, Johnson EC, Kunces LJ, McKenzie AL, Wininger M, Butts CL, Caldwell A, Seal A, McDermott BP, Vingren J, Colburn AT, Wright SS, Iii VL, Armstrong LE, Lee EC. Impact of Nutrient Intake on Hydration Biomarkers Following Exercise and Rehydration Using a Clustering-Based Approach. Nutrients. 2020 Apr 30;12(5):1276. doi: 10.3390/nu12051276. PMID: 32365848; PMCID: PMC7282025.
Goetjen A, Watson M, Lieberman R, Clinton K, Kranzler HR, Covault J. Induced pluripotent stem cell reprogramming-associated methylation at the GABRA2 promoter and chr4p12 GABAA subunit gene expression in the context of alcohol use disorder. Am J Med Genet B Neuropsychiatr Genet. 2020 Dec;183(8):464-474. doi: 10.1002/ajmg.b.32824. Epub 2020 Oct 7. PMID: 33029895; PMCID: PMC8022112.
2019
Cohn R, Thakar K, Lowe A, Ladha FA, Pettinato AM, Romano R, Meredith E, Chen YS, Atamanuk K, Huey BD, Hinson JT. A Contraction Stress Model of Hypertrophic Cardiomyopathy due to Sarcomere Mutations. Stem Cell Reports. 2019 Jan 8;12(1):71-83. doi: 10.1016/j.stemcr.2018.11.015. Epub 2018 Dec 13. PMID: 30554920; PMCID: PMC6335568.
Park S, Brugiolo M, Akerman M, Das S, Urbanski L, Geier A, Kesarwani AK, Fan M, Leclair N, Lin KT, Hu L, Hua I, George J, Muthuswamy SK, Krainer AR, Anczuków O. Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis. Cell Rep. 2019 Nov 26;29(9):2672-2688.e7. doi: 10.1016/j.celrep.2019.10.110. PMID: 31775037; PMCID: PMC6936330.
Chae YK, Viveiros P, Lopes G, Sukhadia B, Sheikh MM, Saravia D, Florou V, Sokol ES, Frampton GM, Chalmers ZR, Ali SM, Ross JS, Chang S, Wang S, Chiec L, Rahbari A, Mohindra N, Villaflor V, Shin SH, Oh M, Anker J, Park LC, Wang V, Chuang J, Park W. Clinical and Immunological Implications of Frameshift Mutations in Lung Cancer. J Thorac Oncol. 2019 Oct;14(10):1807-1817. doi: 10.1016/j.jtho.2019.06.016. Epub 2019 Jun 22. PMID: 31238177.
Dodge-Kafka K, Gildart M, Tokarski K, Kapiloff MS. mAKAPβ signalosomes - A nodal regulator of gene transcription associated with pathological cardiac remodeling. Cell Signal. 2019 Nov;63:109357. doi: 10.1016/j.cellsig.2019.109357. Epub 2019 Jul 9. PMID: 31299211; PMCID: PMC7197268.
Weerasooriya S, DiScipio KA, Darwish AS, Bai P, Weller SK. Herpes simplex virus 1 ICP8 mutant lacking annealing activity is deficient for viral DNA replication. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):1033-1042. doi: 10.1073/pnas.1817642116. Epub 2018 Dec 31. PMID: 30598436; PMCID: PMC6338833.
Al-Naggar IM, Hardy CC, Taweh OG, Grabauskas T, Mulkey DK, Kuchel GA, Smith PP. HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation. J Gerontol A Biol Sci Med Sci. 2019 Feb 15;74(3):325-329. doi: 10.1093/gerona/gly137. PMID: 30124776; PMCID: PMC6376092.
2018
Urbanski LM, Leclair N, Anczuków O. Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics. Wiley Interdiscip Rev RNA. 2018 Jul;9(4):e1476. doi: 10.1002/wrna.1476. Epub 2018 Apr 25. PMID: 29693319; PMCID: PMC6002934.
Wang VG, Kim H, Chuang JH. Whole-exome sequencing capture kit biases yield false negative mutation calls in TCGA cohorts. PLoS One. 2018 Oct 3;13(10):e0204912. doi: 10.1371/journal.pone.0204912. PMID: 30281678; PMCID: PMC6169918.
Choudhary S, Santone E, Yee SP, Lorenzo J, Adams DJ, Goetjen A, McCarthy MB, Mazzocca AD, Pilbeam C. Continuous PTH in Male Mice Causes Bone Loss Because It Induces Serum Amyloid A. Endocrinology. 2018 Jul 1;159(7):2759-2776. doi: 10.1210/en.2018-00265. PMID: 29757436; PMCID: PMC6692876.
Kalsner L, Twachtman-Bassett J, Tokarski K, Stanley C, Dumont-Mathieu T, Cotney J, Chamberlain S. Genetic testing including targeted gene panel in a diverse clinical population of children with autism spectrum disorder: Findings and implications. Mol Genet Genomic Med. 2018 Mar;6(2):171-185. doi: 10.1002/mgg3.354. Epub 2017 Dec 21. PMID: 29271092; PMCID: PMC5902398.
Rheaume BA, Jereen A, Bolisetty M, Sajid MS, Yang Y, Renna K, Sun L, Robson P, Trakhtenberg EF. Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes. Nat Commun. 2018 Jul 17;9(1):2759. doi: 10.1038/s41467-018-05134-3. Erratum in: Nat Commun. 2018 Aug 7;9(1):3203. PMID: 30018341; PMCID: PMC6050223.
2016
Choudhary S, Goetjen A, Estus T, Jacome-Galarza CE, Aguila HL, Lorenzo J, Pilbeam C. Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-stimulated cAMP Signaling in Murine Osteoblasts. J Biol Chem. 2016 Feb 19;291(8):3882-94. doi: 10.1074/jbc.M115.686576. Epub 2015 Dec 23. PMID: 26703472; PMCID: PMC4759168.